The Fall/Winter 2016 collection is set to drop in-store on August 18th across Supreme's NY, LA, London, and Paris locations. If you're in Japan, you'll be able to cop starting August 20th. For everyone shopping online, the webstore goes live on August 25th.
The preview and lookbook sections are already up on the site if you want to plan out your picks ahead of time. Worth checking out the random section too - it's been refreshed with the new season content.